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Explore additional resources describing the challenges of therapeutic delivery and TriNav® as a solution.

Favorable Particle-Fluid Dynamics With PEDD™ and SmartValve® Technology

In a hepatic arterial model, a Pressure-Enabled Drug DeliveryTM device that generated turbulent particle flow demonstrated 62% better microsphere distribution to downstream arterial branches than a traditional microcatheter.
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PEDD™ Approach: Helping to Overcome Barriers to Effective Therapy Delivery

PEDD™ Approach
Evidence demonstrates that the PEDD™ approach offers more precise tumor targeting, increased therapy delivery and better tumor response than traditional microcatheters.
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Drug Infusion Approaches for Solid Liver Tumors

TriNav Device
The challenges to effective therapeutic delivery using traditional drug infusion approaches and the SmartValve™ technology solution.
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Ultrasound Imaging of TriNav Infusion System

Ultrasound Imaging of TriNav Infusion System
See how SmartValve™ technology expands and contracts in sync with the cardiac cycle to help control flow and modulate pressure.
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TriNav Infusion System: Clinical Essentials

TriNav Infusion System: Clinical Essentials
Data from a study comparing the use of end-hole and microvalve infusion catheters in patients undergoing drug-eluting microspheres-TACE for HCC show improved tumor response with the microvalve infusion catheter.
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TriNav Vascular Resistance Modeling

TriNav Vascular Resistance Modeling
Demonstration of Pressure-Enabled Drug Delivery™ (PEDD™) infusion performance.
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Liver Tumor Microenvironment

Our Pressure-Enabled Drug Delivery™ method of administration helps overcome intratumoral pressure to improve therapy delivery in liver tumors.
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Durable Response in Recurrent HCC After Y90 Treatment with TriNav

Y90 Treatment via Pressure-Enabled Drug Delivery in Patient with HCC & Dosimetry Analysis Using MIM SurePlan Y90

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Right Hepatic Glass Y90 Treatment Using TriNav® in Patient with HCC Shows Improved Tumor Targeting Compared to Standard Microcatheter Used in Mapping Procedure

Case Presentation Right Hepatic Glass Y90 Read PDF

Pressure-Enabled Conventional TACE for Hepatocellular Carcinoma: A Case Presentation

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Improved Tumor Perfusion in Hepatocellular Carcinoma

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The Use of TriNav to Improve Perfusion in Setting of Iatrogenic Complication

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Improved Tumor Uptake when Using TriNav® Infusion System in Y-90 Mapping Procedure as Compared to Standard Microcatheter

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Precision and Accuracy of the TriNav® Infusion System in Y-90 Mapping and Therapeutic Delivery

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TriNav Improves Y90 Tumor Perfusion in Multicentric, Multilobar HCC

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PEDD™ DEB-TACE in Patient with HCC

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Improved Perfusion with TriNav® Compared to a Conventional Angiographic Catheter in Metastatic Renal Cell Carcinoma

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Y90 Mapping Procedure using TriNav® in Patient with Metastatic Neuroendocrine Tumor

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Response to Microsphere Embolization Using the TriNav® Infusion System in Hypovascular Leiomyosarcoma Metastases

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Right Hepatic Y90 Radiation Segmentectomy using TriNav® in Patient with Hepatocellular Carcinoma

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Super-Selective DEB-TACE Performed Using TriNav® in Patient with Hepatocellular Carcinoma

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Improved Tumor Uptake when Using a TriNav® Infusion
System in a Y-90 Mapping Procedure

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Highlights: Intra-arterial Pressure-Enabled Drug Delivery™ Significantly Increases Penetration of Glass Microspheres in a Porcine Liver Tumor Model

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Intra-arterial Pressure-Enabled Drug DeliverySignificantly Increases Penetration of Glass Microspheres in a Porcine Liver Tumor Model

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Innovation in Catheter Design for Intra-Arterial Liver Cancer Treatments Results in Favorable Particle-Fluid Dynamics

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Multi-Center Registry Study of the Safety, Feasibility, and Outcomes of Pressure-Enabled Drug Delivery in DEB-TACE for Patients with HCC

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Pressure Enabled Drug Delivery™ — Clinical Evidence. Resonance of multiple clinical studies with different therapeutics

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Pressure-Enabled Drug DeliveryTM Improves Tumor Targeting in Liver Radioembolization with Resin Microspheres

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The Impact of Pressure-Enabled Drug Delivery on Target Volume Particulate Distribution in Liver-Directed Embolotherapy

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A Retrospective Analysis of DEM-TACE Delivered via End-hole Microcatheter vs Pressure-Enabled Drug Delivery in Patients with HCC

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Bridging to Transplant with Dr. Jen Berumen and Dr. Isabel Newton

Episode 64

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Locoregional Therapies for HCC with Dr. Alex Kim

Episode 67

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Targeting the Tumor Microenvironment with Dr. Terence Gade

Episode 76

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IO in Private Practice Part I with Dr. Justin Lee

Episode 91

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IO in Private Practice Part 2 with Dr. Justin Lee

Episode 92

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January 2019

Cardiovascular and Interventional Radiology

End-hole Versus Microvalve Infusion Catheters in Patients Undergoing Drug-Eluting Microspheres-TACE for Solitary Hepatocellular Carcinoma Tumors: A Retrospective Analysis

Titano et al.

Watch the video for more information.

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September 2017

PlOS One

Short-term imaging response after drug-eluting embolic trans-arterial chemoembolization delivered with the Surefire Infusion System® for the treatment of hepatocellular carcinoma

Kim et al.

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May 2015

Journal of Vascular and Interventional Radiology

The Impact of an Antireflux Catheter on Target Volume Particulate Distribution in Liver-Directed Embolotherapy: A Pilot Study

Pasciak et al.

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April 2018

Journal of Vascular and Interventional Radiology

Abstract No. 133 Surefire Infusion System (SIS) hepatocellular carcinoma registry study interim results: a multicenter study of the safety, feasibility, and outcomes of the SIS expandable-tip microcatheter in DEB-TACE

Kapoor et al.

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TriNav® Technical User Guide

Technical User Guide
Helpful information on the device and its use.
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Let us tell you more.

Contact us to learn more about this improved technology for the proprietary PEDD method.

References

1. TriSalus TriNav® Infusion System, Instructions for Use.